81 Split Products of Fibrinogen in Cord Serum

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Quantitative estimation of split products of fibrinogen in human serum, relation to diagnosis and treatment.

tion of fibrinogen or fibrin by pl ismii ,1’2 l)\’ trYI)SIfl and other proteolytic enzymes’ or even PerhlaPs l)V hydrolytic enzymes ( ? cathepsins ) derived from neutrophilic leukocytes.4 In this report these split products are considered to be 1)clrtially digested fibrinogen or fibrin fragments which react with antifibrinogen ( or antifibrin ) sera and are incoagulable with thrombin. They inhibit

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Serum and urinary fibrin-fibrinogen degradation products in glomerulonephritis.

The serum and urine concentrations of fibrin/fibrinogen degradation products (F.D.P.) were estimated in 172 patients with glomerulonephritis. In each case the diagnosis was established on the basis of clinical, renal histological, and ultrastructural findings. Serum F.D.P. concentrations were often raised in all types of glomerulonephritis, though more consistently in active proliferative forms...

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Fibrinogen-fibrin degradation products.

The identification of the molecular structure of fibrinogen has given a better understanding of many clinical conditions associated with abnormalities of fibrinogen. Proteolysis of fibrinogen or fibrin by its natural lytic enzyme, plasmin, leads to the formation of degradation products which are of great importance in the laboratory diagnosis of many pathological conditions. The biochemical and...

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Serum levels of fibrin-fibrinogen degradation products in the haemolytic-uraemic syndrome.

Burgio, G. R., and Vaccaro, R. (1966). Porpora nodulare del lattante. Gazzetta Sanitaria, 37, 275. Goldman, H. I., and Amadio, P. (1969). Vitamin K deficiency after the newbom period. Pediatrics, 44, 745. -. and Deposito, F. (1966). Hypoprothrombinemic bleeding in young infants. American Journal of Diseases of Children, 111, 430. Rapoport, S., and Dodd, K. (1946). Hypoprothrombinemia in infants...

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Fibrin-fibrinogen degradation products in cerebrospinal fluid.

An increase in low molecular weight fibrin-fibrinogen degradation products (FDP) was demonstrated in cerebrospinal fluid (CSF) from 17 of 18 patients with bacterial or viral meningitis compared with 29 patients without meningitis. The CSF also showed an increase in coagulation proteins of molecular weight less than 90000 (factors VII, IX, and plasminogen) but did not contain fibrinogen (MW 3400...

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ژورنال

عنوان ژورنال: Pediatric Research

سال: 1967

ISSN: 0031-3998,1530-0447

DOI: 10.1203/00006450-196705000-00088